Abstract / truncated to 115 words (read the full abstract)

Magnetic Resonance Spectroscopy (MRS) is a technique used in fundamental research and in clinical environments. During recent years, clinical application of MRS gained importance, especially as a non-invasive tool for diagnosis and therapy monitoring of brain and prostate tumours. The most important asset of MRS is its ability to determine the concentration of chemical substances non-invasively. To extract relevant signal parameters, MRS data have to be quantified. This usually doesn¢t prove to be straightforward since in vivo MRS signals are characterized by poor signal-to-noise ratios, overlapping peaks, acquisition related artefacts and the presence of disturbing components (e.g. residual water in proton spectra). The work presented in this thesis aims to improve the quantification in different ... toggle 1 keyword

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