Nowadays, Nuclear Magnetic Resonance (NMR) is widely used in oncology as a non-invasive diagnostic tool in order to detect the presence of tumor regions in the human body. An application of NMR is Magnetic Resonance Imaging, which is applied in routine clinical practice to localize tumors and determine their size. Magnetic Resonance Imaging is able to provide an initial diagnosis, but its ability to delineate anatomical and pathological information is significantly improved by its combination with another NMR application, namely Magnetic Resonance Spectroscopy. The latter reveals information on the biochemical profile tissues, thereby allowing clinicians and radiologists to identify in a non{invasive way the different tissue types characterizing the sample under investigation, and to study the biochemical changes underlying a pathological situation. In particular, an NMR application exists which provides spatial as well as biochemical information. This application is called ...

This Thesis is focused on the use of automatic speaker recognition systems for forensic identification, in what is called forensic automatic speaker recognition. More generally, forensic identification aims at individualization, defined as the certainty of distinguishing an object or person from any other in a given population. This objective is followed by the analysis of the forensic evidence, understood as the comparison between two samples of material, such as glass, blood, speech, etc. An automatic speaker recognition system can be used in order to perform such comparison between some recovered speech material of questioned origin (e.g., an incriminating wire-tapping) and some control speech material coming from a suspect (e.g., recordings acquired in police facilities). However, the evaluation of such evidence is not a trivial issue at all. In fact, the debate about the presentation of forensic evidence in a court ...

This thesis discusses approaches and techniques to convert Sparsely-Sampled Light Fields (SSLFs) into Densely-Sampled Light Fields (DSLFs), which can be used for visualization on 3DTV and Virtual Reality (VR) devices. Exemplarily, a movable 1D large-scale light field acquisition system for capturing SSLFs in real-world environments is evaluated. This system consists of 24 sparsely placed RGB cameras and two Kinect V2 sensors. The real-world SSLF data captured with this setup can be leveraged to reconstruct real-world DSLFs. To this end, three challenging problems require to be solved for this system: (i) how to estimate the rigid transformation from the coordinate system of a Kinect V2 to the coordinate system of an RGB camera; (ii) how to register the two Kinect V2 sensors with a large displacement; (iii) how to reconstruct a DSLF from a SSLF with moderate and large disparity ranges. ...

Progressive developments in computing and sensor technologies during the past decades have enabled the formulation of increasingly advanced problems in statistical inference and signal processing. The thesis is concerned with statistical estimation methods, and is divided into three parts with focus on two different areas: sensor fusion and sparse signal processing. The first part introduces the well-established Bayesian, Fisherian and least-squares estimation frameworks, and derives new estimators. Specifically, the Bayesian framework is applied in two different classes of estimation problems: scenarios in which (i) the signal covariances themselves are subject to uncertainties, and (ii) distance bounds are used as side information. Applications include localization, tracking and channel estimation. The second part is concerned with the extraction of useful information from multiple sensors by exploiting their joint properties. Two sensor configurations are considered here: (i) a monocular camera and an inertial ...

This thesis develops new mathematical theory and presents novel recovery algorithms for discrete linear dynamical systems (LDS) with sparsity constraints on either control inputs or initial state. The recovery problems in this framework manifest as the problem of reconstructing one or more sparse signals from a set of noisy underdetermined linear measurements. The goal of our work is to design algorithms for sparse signal recovery which can exploit the underlying structure in the measurement matrix and the unknown sparse vectors, and to analyze the impact of these structures on the efficacy of the recovery. We answer three fundamental and interconnected questions on sparse signal recovery problems that arise in the context of LDS. First, what are necessary and sufficient conditions for the existence of a sparse solution? Second, given that a sparse solution exists, what are good low-complexity algorithms that ...

Obstructive sleep apnea (OSA) is among the most prevalent sleep disorders, which is estimated to affect 6 %−19 % of women and 13 %−33 % of men. Besides daytime sleepiness, impaired cognitive functioning and an increased risk for accidents, OSA may lead to obesity, diabetes and cardiovascular diseases (CVD) on the long term. Its prevalence is only expected to rise, as it is linked to aging and excessive body fat. Nevertheless, many patients remain undiagnosed and untreated due to the cumbersome clinical diagnostic procedures. For this, the patient is required to sleep with an extensive set of body attached sensors. In addition, the recordings only provide a single night perspective on the patient in an uncomfortable, and often unknown, environment. Thus, large scale monitoring at home is desired with comfortable sensors, which can stay in place for several nights. To ...

Super-resolution (SR) is a filtering technique that combines a sequence of under-sampled and degraded low-resolution images to produce an image at a higher resolution. The reconstruction takes advantage of the additional spatio-temporal data available in the sequence of images portraying the same scene. The fundamental problem addressed in super-resolution is a typical example of an inverse problem, wherein multiple low-resolution (LR)images are used to solve for the original high-resolution (HR) image. Super-resolution has already proved useful in many practical cases where multiple frames of the same scene can be obtained, including medical applications, satellite imaging and astronomical observatories. The application of super resolution filtering in consumer cameras and mobile devices shall be possible in the future, especially that the computational and memory resources in these devices are increasing all the time. For that goal, several research problems need to be ...

Automatic face recognition has attracted a lot of attention not only because of the large number of practical applications where human identification is needed but also due to the technical challenges involved in this problem: large variability in facial appearance, non-linearity of face manifolds and high dimensionality are some the most critical handicaps. In order to deal with the above mentioned challenges, there are two possible strategies: the first is to construct a “good” feature space in which the manifolds become simpler (more linear and more convex). This scheme usually comprises two levels of processing: (1) normalize images geometrically and photometrically and (2) extract features that are stable with respect to these variations (such as those based on Gabor filters). The second strategy is to use classification structures that are able to deal with non-linearities and to generalize properly. To ...

In this PhD thesis the problem of detection and classification of stationary targets in Through-the-Wall Radar Imaging is considered. A multiple-view framework is used in which a 3D scene of interest is imaged from a set of vantage points. By doing so, clutter and noise is strongly suppressed and target detectability increased. In target detection, centralized as well as decentralized frameworks for simultaneous image fusion and detection are examined. The practical case when no prior knowledge on image statistics is available and all inference must be drawn from the data at hand is specifically considered. An adaptive detection scheme is proposed which iteratively adapts in a non-stationary environment. Optimal configurations for this scheme are derived based on morphological operations which allow for automatic and reliable target detection. In a decentralized framework, local decisions are transmitted to a fusion center to ...

In this thesis, we present novel methods to enhance speech corrupted by noise. All methods are based on the processing of complex-valued spectral data. First, kernel principal component analysis (PCA) for speech enhancement is proposed. Subsequently, a simplification of kernel PCA, called pre-image iterations (PI), is derived. This method computes enhanced feature vectors iteratively by linear combination of noisy feature vectors. The weighting for the linear combination is found by a kernel function that measures the similarity between the feature vectors. The kernel variance is a key parameter for the degree of de-noising and has to be set according to the signal-to-noise ratio (SNR). Initially, PI were proposed for speech corrupted by additive white Gaussian noise. To be independent of knowledge about the SNR and to generalize to other stationary noise types, PI are extended by automatic determination of the ...

Hyperspectral (HS) imaging, which consists of acquiring a same scene in several hundreds of contiguous spectral bands (a three dimensional data cube), has opened a new range of relevant applications, such as target detection [MS02], classification [C.-03] and spectral unmixing [BDPD+12]. However, while HS sensors provide abundant spectral information, their spatial resolution is generally more limited. Thus, fusing the HS image with other highly resolved images of the same scene, such as multispectral (MS) or panchromatic (PAN) images is an interesting problem. The problem of fusing a high spectral and low spatial resolution image with an auxiliary image of higher spatial but lower spectral resolution, also known as multi-resolution image fusion, has been explored for many years [AMV+11]. From an application point of view, this problem is also important as motivated by recent national programs, e.g., the Japanese next-generation space-borne ...

Single-pixel imaging is a recent paradigm that allows the acquisition of images at reasonably low cost by exploiting hardware compression of the data. The architecture of a single-pixel camera consists of only two elements: a spatial light modulator, and a single-point detector. The key idea is to measure the projection at the detector (i.e., the inner product) of the scene under view -the image- with some patterns. The post-processing of a sequence of measurements obtained with different patterns permits the restoring of the desired image. Single-pixel imaging has several advantages, which are of interest for different applications, and especially in the biomedical field. In particular, a time-resolved single-pixel imaging system benefits fluorescence lifetime sensing. Such a set-up can be coupled to a spectrometer, to supplement the lifetime with spectral information. However, the main limitation of single-pixel imaging is the speed ...

Recent improvements in the development of inertial and visual sensors allow building small, lightweight, and cheap motion capture systems, which are becoming a standard feature of smartphones and personal digital assistants. This dissertation describes developments of new motion sensing strategies using the inertial and inertial-visual sensors. The thesis contributions are presented in two parts. The first part focuses mainly on the use of inertial measurement units. First, the problem of sensor calibration is addressed and a low-cost and accurate method to calibrate the accelerometer cluster of this unit is proposed. The method is based on the maximum likelihood estimation framework, which results in a minimum variance unbiased estimator.Then using the inertial measurement unit, a probabilistic user-independent method is proposed for pedestrian activity classification and gait analysis.The work targets two groups of applications including human activity classificationand joint human activity and ...

Compressed sensing (CS) is a recently introduced signal acquisition framework that goes against the traditional Nyquist sampling paradigm. CS demonstrates that a sparse, or compressible, signal can be acquired using a low rate acquisition process. Since noise is always present in practical data acquisition systems, sensing and reconstruction methods are developed assuming a Gaussian (light-tailed) model for the corrupting noise. However, when the underlying signal and/or the measurements are corrupted by impulsive noise, commonly employed linear sampling operators, coupled with Gaussian-derived reconstruction algorithms, fail to recover a close approximation of the signal. This dissertation develops robust sampling and reconstruction methods for sparse signals in the presence of impulsive noise. To achieve this objective, we make use of robust statistics theory to develop appropriate methods addressing the problem of impulsive noise in CS systems. We develop a generalized Cauchy distribution (GCD) ...

Compressed Sensing (CS) is a widely used technique for efficient signal acquisition, in which a very small number of (possibly noisy) linear measurements of an unknown signal vector are taken via multiplication with a designed ‘sensing matrix’ in an application-specific manner, and later recovered by exploiting the sparsity of the signal vector in some known orthonormal basis and some special properties of the sensing matrix which allow for such recovery. We study three new applications of CS, each of which poses a unique challenge in a different aspect of it, and propose novel techniques to solve them, advancing the field of CS. Each application involves a unique combination of realistic assumptions on the measurement noise model and the signal, and a unique set of algorithmic challenges. We frame Pooled RT-PCR Testing for COVID-19 – wherein RT-PCR (Reverse Transcription Polymerase Chain ...